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Bayesian molecular dating is widely used to study evolutionary timescales. This procedure usually involves phylogenetic analysis of nucleotide sequence data, with fossil-based calibrations applied as age constraints on internal nodes of the tree. An alternative approach is tip-dating, which explicitly includes fossil data in the analysis. This can be done, for example, through the joint analysis of molecular data from present-day taxa and morphological data from both extant and fossil taxa. In the context of tip-dating, an important development has been the fossilized birth—death process, which allows non-contemporaneous tips and sampled ancestors while providing a model of lineage diversification for the prior on the tree topology and internal node times. However, tip-dating with fossils faces a number of considerable challenges, especially, those associated with fossil sampling and evolutionary models for morphological characters. We conducted a simulation study to evaluate the performance of tip-dating using the fossilized birth—death model.

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A new statistical method for estimating divergence dates of species from DNA sequence data by a molecular clock approach is developed. This method takes into account effectively the information contained in a set of DNA sequence data. The molecular clock of mitochondrial DNA mtDNA was calibrated by setting the date of divergence between primates and ungulates at the Cretaceous-Tertiary boundary 65 million years ago , when the extinction of dinosaurs occurred.

A generalized leastsquares method was applied in fitting a model to mtDNA sequence data, and the clock gave dates of Although there is some uncertainty in the clock, this dating may pose a problem for the widely believed hypothesis that the bipedal creature Australopithecus afarensis , which lived some 3. Another likelier possibility is that mtDNA was transferred through hybridization between a proto-human and a protochimpanzee after the former had developed bipedalism.

Download to read the full article text. Folia Primatol Basel — Google Scholar. Science — Nature —

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position is correct (as the majority of scholars since Aptowitzer claim)40 we are left simply with the absence of a witness to the early dating of MK, furnishing no.

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